Neuroimaging Laboratory
University of Campinas
Relaxo LNI Introduction
Relaxo LNI is a user-friendly software developed by the Neuroimaging Laboratory (UNICAMP) for T2 multi-echo relaxometry analysis. The tool processes T2 multi-echo DICOM images, estimates a whole-brain quantitative T2 map, and supports manual sub-region segmentation.
Users may optionally load a T1-weighted image (T1WI) for registration with T2 data and define regions of interest (ROIs) using different background visualization options: T2 (any echo), T1WI (if provided), contrast-inverted T2, or the quantitative T2 map.
The software exports quantitative tables of segmented regions (in .xlsx format), quantitative maps, and ROI masks.
Relaxo LNI Team
Developer and coordinator
Brunno M. de Campos, Ph.D.
Theoretical Collaborators
Raphael F Casseb, Ph.D; Fernando Cendes, MD, Ph.D.
Relaxo LNI Requirement
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MS Windows operating system
Relaxo LNI currently has the following functionalities:
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Open raw DICOM multi-echoes T2 images
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Whole-brain T2 estimation (exportable image in NIfTI)
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Manual segmentation using free-hand or circular ROI tools (ROIs exportable in NIfTI)
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Multiple visualization options: raw T2 (any echo), T2 with inverted contrast (make the T2 similar to a T1WI), quantified T2, and registered T1 (the tool performs the affine registration automatically)
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You can draw your ROIs in several slices, creating a volume of interest (VOI). After drawing, you decide which ROI (slice) will be "captured" for the report, quantifications, and exportable NIfTI outputs.
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You will always have the ROI intensities histogram available (considering the background image, whatever you choose). This provides information that enables ROI uniformity during the drawing procedure.
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During the drawing procedure, the tool provides the T2 value, all ROI echoes values, and the relaxation plot in REAL-TIME!
Relaxo LNI Interface and output examples:
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